ChloroquineV1, France, Analysis, bibRecord, 000132

Impact of hydroxychloroquine on preterm delivery and intrauterine growth restriction in pregnant women with systemic lupus erythematosus: a descriptive cohort study

Identifieur interne : 000132 ( France/Analysis ); précédent : 000131; suivant : 000133

Impact of hydroxychloroquine on preterm delivery and intrauterine growth restriction in pregnant women with systemic lupus erythematosus: a descriptive cohort study

Auteurs : M. Leroux ; Cyrille Desveaux [France] ; M. Parcevaux ; B. Juliac ; Jean-Bernard Gouyon [Réunion] ; D. Dallay ; J-L Pellegrin ; Malik Boukerrou [Réunion] ; P. Blanco ; E. Lazaro

Source :

Lupus [ 0961-2033 ] ; 2015-11.

RBID : Hal:hal-01477005

English descriptors

mix :
- Périnatalité.

Abstract

ObjectiveThe aim of this study was to evaluate the effect of hydroxychloroquine (HCQ) on fetal preterm delivery and intrauterine growth restriction (IUGR) in a cohort of pregnant women with systemic lupus erythematosus (SLE).MethodsOver an 11-year period (January 1, 2001 to December 31, 2011), all women with SLE and admitted to deliver after 22 weeks of gestation to Bordeaux University Hospital (France), were retrospectively enrolled in the present study. The population was then split into two groups based on the treatment they received: HCQ exposed (HCQ+) versus HCQ non-exposed (HCQ?) group.Results118 pregnancies were included, 41 in the HCQ+ group and 77 in the HCQ? group. The rate of adverse fetal outcome was significantly lower in the HCQ+ group (p?=?0.001), particularly in terms of preterm delivery, 15.8 % versus 44.2 % (p?=?0.006), and IUGR, 10.5 % versus 28.6 % (p?=?0.03). No adverse outcomes were reported in the HCQ+ group.ConclusionHCQ reduces neonatal morbidity in women with SLE by significantly decreasing the rate of prematurity and intrauterine growth restriction.

Url:

https://hal.univ-reunion.fr/hal-01477005

DOI: 10.1177/0961203315591027

Affiliations:

France, Réunion

Links toward previous steps (curation, corpus...)

to stream Hal, to step Corpus: 000127
to stream Hal, to step Curation: 000127
to stream Hal, to step Checkpoint: 000087
to stream Main, to step Merge: 000E41
to stream Main, to step Curation: 000E40
to stream Main, to step Exploration: 000E40
to stream France, to step Extraction: 000132

Links to Exploration step

Hal:hal-01477005

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Impact of hydroxychloroquine on preterm delivery and intrauterine growth restriction in pregnant women with systemic lupus erythematosus: a descriptive cohort study</title>
<author><name sortKey="Leroux, M" sort="Leroux, M" uniqKey="Leroux M" first="M" last="Leroux">M. Leroux</name>
</author>
<author><name sortKey="Desveaux, Cyrille" sort="Desveaux, Cyrille" uniqKey="Desveaux C" first="Cyrille" last="Desveaux">Cyrille Desveaux</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-192733" status="VALID">          <orgName>Service de gynécologie-obstétrique [La réunion]</orgName>
          <desc>            <address>              <addrLine>Saint-Pierre, La réunion</addrLine>
              <country key="FR"></country>
            </address>
          </desc>
          <listRelation>            <relation active="#struct-301275" type="direct"></relation>
            <relation active="#struct-302120" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-301275" type="direct"><org type="institution" xml:id="struct-301275" status="VALID">          <orgName>Groupe Hospitalier Sud</orgName>
          <desc>            <address>              <country key="FR"></country>
            </address>
          </desc>
        </org>
</tutelle>
<tutelle active="#struct-302120" type="direct"><org type="institution" xml:id="struct-302120" status="VALID">          <orgName>CHR La réunion</orgName>
          <desc>            <address>              <country key="FR"></country>
            </address>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Parcevaux, M" sort="Parcevaux, M" uniqKey="Parcevaux M" first="M" last="Parcevaux">M. Parcevaux</name>
</author>
<author><name sortKey="Juliac, B" sort="Juliac, B" uniqKey="Juliac B" first="B" last="Juliac">B. Juliac</name>
</author>
<author><name sortKey="Gouyon, Jean Bernard" sort="Gouyon, Jean Bernard" uniqKey="Gouyon J" first="Jean-Bernard" last="Gouyon">Jean-Bernard Gouyon</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-418885" status="VALID">          <orgName>Centre d'Études Périnatales de l'Océan Indien</orgName>
          <orgName type="acronym">CEPOI</orgName>
          <desc>            <address>              <country key="RE"></country>
            </address>
          </desc>
          <listRelation>            <relation name="EA" active="#struct-300316" type="direct"></relation>
            <relation active="#struct-351465" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle name="EA" active="#struct-300316" type="direct"><org type="institution" xml:id="struct-300316" status="VALID">          <orgName>Université de La Réunion</orgName>
          <orgName type="acronym">UR</orgName>
          <desc>            <address>              <addrLine>15, avenue René Cassin - CS92003 -97744 Saint Denis Cedex 9</addrLine>
              <country key="RE"></country>
            </address>
            <ref type="url">http://www.univ-reunion.fr</ref>
          </desc>
        </org>
</tutelle>
<tutelle active="#struct-351465" type="direct"><org type="institution" xml:id="struct-351465" status="VALID">          <orgName>Centre Hospitalier Universitaire de La Réunion</orgName>
          <orgName type="acronym">CHU La Réunion</orgName>
          <desc>            <address>              <country key="RE"></country>
            </address>
            <ref type="url">http://www.chu-reunion.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>Réunion</country>
</affiliation>
</author>
<author><name sortKey="Dallay, D" sort="Dallay, D" uniqKey="Dallay D" first="D" last="Dallay">D. Dallay</name>
</author>
<author><name sortKey="Pellegrin, J L" sort="Pellegrin, J L" uniqKey="Pellegrin J" first="J-L" last="Pellegrin">J-L Pellegrin</name>
</author>
<author><name sortKey="Boukerrou, Malik" sort="Boukerrou, Malik" uniqKey="Boukerrou M" first="Malik" last="Boukerrou">Malik Boukerrou</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-418885" status="VALID">          <orgName>Centre d'Études Périnatales de l'Océan Indien</orgName>
          <orgName type="acronym">CEPOI</orgName>
          <desc>            <address>              <country key="RE"></country>
            </address>
          </desc>
          <listRelation>            <relation name="EA" active="#struct-300316" type="direct"></relation>
            <relation active="#struct-351465" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle name="EA" active="#struct-300316" type="direct"><org type="institution" xml:id="struct-300316" status="VALID">          <orgName>Université de La Réunion</orgName>
          <orgName type="acronym">UR</orgName>
          <desc>            <address>              <addrLine>15, avenue René Cassin - CS92003 -97744 Saint Denis Cedex 9</addrLine>
              <country key="RE"></country>
            </address>
            <ref type="url">http://www.univ-reunion.fr</ref>
          </desc>
        </org>
</tutelle>
<tutelle active="#struct-351465" type="direct"><org type="institution" xml:id="struct-351465" status="VALID">          <orgName>Centre Hospitalier Universitaire de La Réunion</orgName>
          <orgName type="acronym">CHU La Réunion</orgName>
          <desc>            <address>              <country key="RE"></country>
            </address>
            <ref type="url">http://www.chu-reunion.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>Réunion</country>
</affiliation>
</author>
<author><name sortKey="Blanco, P" sort="Blanco, P" uniqKey="Blanco P" first="P" last="Blanco">P. Blanco</name>
</author>
<author><name sortKey="Lazaro, E" sort="Lazaro, E" uniqKey="Lazaro E" first="E" last="Lazaro">E. Lazaro</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">HAL</idno>
<idno type="RBID">Hal:hal-01477005</idno>
<idno type="halId">hal-01477005</idno>
<idno type="halUri">https://hal.univ-reunion.fr/hal-01477005</idno>
<idno type="url">https://hal.univ-reunion.fr/hal-01477005</idno>
<idno type="doi">10.1177/0961203315591027</idno>
<date when="2015-11">2015-11</date>
<idno type="wicri:Area/Hal/Corpus">000127</idno>
<idno type="wicri:Area/Hal/Curation">000127</idno>
<idno type="wicri:Area/Hal/Checkpoint">000087</idno>
<idno type="wicri:explorRef" wicri:stream="Hal" wicri:step="Checkpoint">000087</idno>
<idno type="wicri:doubleKey">0961-2033:2015:Leroux M:impact:of:hydroxychloroquine</idno>
<idno type="wicri:Area/Main/Merge">000E41</idno>
<idno type="wicri:Area/Main/Curation">000E40</idno>
<idno type="wicri:Area/Main/Exploration">000E40</idno>
<idno type="wicri:Area/France/Extraction">000132</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Impact of hydroxychloroquine on preterm delivery and intrauterine growth restriction in pregnant women with systemic lupus erythematosus: a descriptive cohort study</title>
<author><name sortKey="Leroux, M" sort="Leroux, M" uniqKey="Leroux M" first="M" last="Leroux">M. Leroux</name>
</author>
<author><name sortKey="Desveaux, Cyrille" sort="Desveaux, Cyrille" uniqKey="Desveaux C" first="Cyrille" last="Desveaux">Cyrille Desveaux</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-192733" status="VALID">          <orgName>Service de gynécologie-obstétrique [La réunion]</orgName>
          <desc>            <address>              <addrLine>Saint-Pierre, La réunion</addrLine>
              <country key="FR"></country>
            </address>
          </desc>
          <listRelation>            <relation active="#struct-301275" type="direct"></relation>
            <relation active="#struct-302120" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-301275" type="direct"><org type="institution" xml:id="struct-301275" status="VALID">          <orgName>Groupe Hospitalier Sud</orgName>
          <desc>            <address>              <country key="FR"></country>
            </address>
          </desc>
        </org>
</tutelle>
<tutelle active="#struct-302120" type="direct"><org type="institution" xml:id="struct-302120" status="VALID">          <orgName>CHR La réunion</orgName>
          <desc>            <address>              <country key="FR"></country>
            </address>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Parcevaux, M" sort="Parcevaux, M" uniqKey="Parcevaux M" first="M" last="Parcevaux">M. Parcevaux</name>
</author>
<author><name sortKey="Juliac, B" sort="Juliac, B" uniqKey="Juliac B" first="B" last="Juliac">B. Juliac</name>
</author>
<author><name sortKey="Gouyon, Jean Bernard" sort="Gouyon, Jean Bernard" uniqKey="Gouyon J" first="Jean-Bernard" last="Gouyon">Jean-Bernard Gouyon</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-418885" status="VALID">          <orgName>Centre d'Études Périnatales de l'Océan Indien</orgName>
          <orgName type="acronym">CEPOI</orgName>
          <desc>            <address>              <country key="RE"></country>
            </address>
          </desc>
          <listRelation>            <relation name="EA" active="#struct-300316" type="direct"></relation>
            <relation active="#struct-351465" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle name="EA" active="#struct-300316" type="direct"><org type="institution" xml:id="struct-300316" status="VALID">          <orgName>Université de La Réunion</orgName>
          <orgName type="acronym">UR</orgName>
          <desc>            <address>              <addrLine>15, avenue René Cassin - CS92003 -97744 Saint Denis Cedex 9</addrLine>
              <country key="RE"></country>
            </address>
            <ref type="url">http://www.univ-reunion.fr</ref>
          </desc>
        </org>
</tutelle>
<tutelle active="#struct-351465" type="direct"><org type="institution" xml:id="struct-351465" status="VALID">          <orgName>Centre Hospitalier Universitaire de La Réunion</orgName>
          <orgName type="acronym">CHU La Réunion</orgName>
          <desc>            <address>              <country key="RE"></country>
            </address>
            <ref type="url">http://www.chu-reunion.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>Réunion</country>
</affiliation>
</author>
<author><name sortKey="Dallay, D" sort="Dallay, D" uniqKey="Dallay D" first="D" last="Dallay">D. Dallay</name>
</author>
<author><name sortKey="Pellegrin, J L" sort="Pellegrin, J L" uniqKey="Pellegrin J" first="J-L" last="Pellegrin">J-L Pellegrin</name>
</author>
<author><name sortKey="Boukerrou, Malik" sort="Boukerrou, Malik" uniqKey="Boukerrou M" first="Malik" last="Boukerrou">Malik Boukerrou</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-418885" status="VALID">          <orgName>Centre d'Études Périnatales de l'Océan Indien</orgName>
          <orgName type="acronym">CEPOI</orgName>
          <desc>            <address>              <country key="RE"></country>
            </address>
          </desc>
          <listRelation>            <relation name="EA" active="#struct-300316" type="direct"></relation>
            <relation active="#struct-351465" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle name="EA" active="#struct-300316" type="direct"><org type="institution" xml:id="struct-300316" status="VALID">          <orgName>Université de La Réunion</orgName>
          <orgName type="acronym">UR</orgName>
          <desc>            <address>              <addrLine>15, avenue René Cassin - CS92003 -97744 Saint Denis Cedex 9</addrLine>
              <country key="RE"></country>
            </address>
            <ref type="url">http://www.univ-reunion.fr</ref>
          </desc>
        </org>
</tutelle>
<tutelle active="#struct-351465" type="direct"><org type="institution" xml:id="struct-351465" status="VALID">          <orgName>Centre Hospitalier Universitaire de La Réunion</orgName>
          <orgName type="acronym">CHU La Réunion</orgName>
          <desc>            <address>              <country key="RE"></country>
            </address>
            <ref type="url">http://www.chu-reunion.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>Réunion</country>
</affiliation>
</author>
<author><name sortKey="Blanco, P" sort="Blanco, P" uniqKey="Blanco P" first="P" last="Blanco">P. Blanco</name>
</author>
<author><name sortKey="Lazaro, E" sort="Lazaro, E" uniqKey="Lazaro E" first="E" last="Lazaro">E. Lazaro</name>
</author>
</analytic>
<idno type="DOI">10.1177/0961203315591027</idno>
<series><title level="j">Lupus</title>
<idno type="ISSN">0961-2033</idno>
<imprint><date type="datePub">2015-11</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="mix" xml:lang="en"><term>Périnatalité</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">              <p>ObjectiveThe aim of this study was to evaluate the effect of hydroxychloroquine (HCQ) on fetal preterm delivery and intrauterine growth restriction (IUGR) in a cohort of pregnant women with systemic lupus erythematosus (SLE).MethodsOver an 11-year period (January 1, 2001 to December 31, 2011), all women with SLE and admitted to deliver after 22 weeks of gestation to Bordeaux University Hospital (France), were retrospectively enrolled in the present study. The population was then split into two groups based on the treatment they received: HCQ exposed (HCQ+) versus HCQ non-exposed (HCQ?) group.Results118 pregnancies were included, 41 in the HCQ+ group and 77 in the HCQ? group. The rate of adverse fetal outcome was significantly lower in the HCQ+ group (p?=?0.001), particularly in terms of preterm delivery, 15.8 % versus 44.2 % (p?=?0.006), and IUGR, 10.5 % versus 28.6 % (p?=?0.03). No adverse outcomes were reported in the HCQ+ group.ConclusionHCQ reduces neonatal morbidity in women with SLE by significantly decreasing the rate of prematurity and intrauterine growth restriction.</p>
            </div>
</front>
</TEI>
<affiliations><list><country><li>France</li>
<li>Réunion</li>
</country>
</list>
<tree><noCountry><name sortKey="Blanco, P" sort="Blanco, P" uniqKey="Blanco P" first="P" last="Blanco">P. Blanco</name>
<name sortKey="Dallay, D" sort="Dallay, D" uniqKey="Dallay D" first="D" last="Dallay">D. Dallay</name>
<name sortKey="Juliac, B" sort="Juliac, B" uniqKey="Juliac B" first="B" last="Juliac">B. Juliac</name>
<name sortKey="Lazaro, E" sort="Lazaro, E" uniqKey="Lazaro E" first="E" last="Lazaro">E. Lazaro</name>
<name sortKey="Leroux, M" sort="Leroux, M" uniqKey="Leroux M" first="M" last="Leroux">M. Leroux</name>
<name sortKey="Parcevaux, M" sort="Parcevaux, M" uniqKey="Parcevaux M" first="M" last="Parcevaux">M. Parcevaux</name>
<name sortKey="Pellegrin, J L" sort="Pellegrin, J L" uniqKey="Pellegrin J" first="J-L" last="Pellegrin">J-L Pellegrin</name>
</noCountry>
<country name="France"><noRegion><name sortKey="Desveaux, Cyrille" sort="Desveaux, Cyrille" uniqKey="Desveaux C" first="Cyrille" last="Desveaux">Cyrille Desveaux</name>
</noRegion>
</country>
<country name="Réunion"><noRegion><name sortKey="Gouyon, Jean Bernard" sort="Gouyon, Jean Bernard" uniqKey="Gouyon J" first="Jean-Bernard" last="Gouyon">Jean-Bernard Gouyon</name>
</noRegion>
<name sortKey="Boukerrou, Malik" sort="Boukerrou, Malik" uniqKey="Boukerrou M" first="Malik" last="Boukerrou">Malik Boukerrou</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/France/Analysis

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000132 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/France/Analysis/biblio.hfd -nk 000132 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    ChloroquineV1
   |flux=    France
   |étape=   Analysis
   |type=    RBID
   |clé=     Hal:hal-01477005
   |texte=   Impact of hydroxychloroquine on preterm delivery and intrauterine growth restriction in pregnant women with systemic lupus erythematosus: a descriptive cohort study
}}

This area was generated with Dilib version V0.6.33.
Data generation: Wed Mar 25 22:43:59 2020. Site generation: Sun Jan 31 12:44:45 2021

	Serveur d'exploration Chloroquine
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration Chloroquine

Impact of hydroxychloroquine on preterm delivery and intrauterine growth restriction in pregnant women with systemic lupus erythematosus: a descriptive cohort study

Impact of hydroxychloroquine on preterm delivery and intrauterine growth restriction in pregnant women with systemic lupus erythematosus: a descriptive cohort study

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri